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Methotrexate

Methotrexate is prescribed for the treatment of several conditions including certain types of cancers (breast, skin, head and neck, or lung) and psoriasis and rheumatoid arthritis.
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Methotrexate is prescribed for the treatment of several conditions including certain types of cancers (breast, skin, head and neck, or lung) and psoriasis and rheumatoid arthritis.

However, your doctor may also prescribe Methotrexate for other conditions if found appropriate.

How to use Methotrexate

The ideal way to use Methotrexate is to follow the instructions of your doctor. An alternative way is to check the medicine label for dosage instructions.

Methotrexate may be taken with or without a meal. Methotrexate should be taken with a full glass of water.

Preferably, Methotrexate should be taken at the same time each day to help maintain a regular routine for taking it.

It may be weeks before you start noticing the effects of the drug.

You must not stop taking Methotrexate without consulting your doctor even if you attain relief after a short while post starting treatment.

Drug Class and Mechanism

Methotrexate is an antimetabolite that works by inhibiting an enzyme needed for cell growth. This in turn stops cancer cells from replicating and spreading in the body. Its working to stop inflammation in rheumatoid arthritis is unknown.

Missed Dose

It is important that you maintain a strict schedule for taking Methotrexate to ensure that you do not miss any doses. But if you do, then you may take it as soon as you remember provided that you space out the next dosage accordingly.

On the other hand, if it is almost time for the next dose, then omit this dose and continue with your normal dosage schedule.

Never consume two doses to compensate for a missed dosage.

Storage

Store Methotrexate at 77 degrees F (15 and 25 Degrees), at room temperature. Ensure that you protect it from direct exposure to heat/moisture/light and from the reach of children and pets.

Avoid storing Methotrexate in the bathroom.
Most drugs have some kind of side effects associated with them. However, most people do not experience them at all or experience just mild side effects which subside as the body adjusts to the medicine.

Some of the mild but common side effects of Methotrexate are dizziness; headache; loss of appetite; mild hair loss; nausea; stomach pain or upset; tiredness; vomiting.

However, please contact your doctor if these side effects do not go away after a while or start bothering you.

On the other hand, Methotrexate may also cause some severe side effects like Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the urine; calf or leg pain or swelling; change in the amount of urine; chest pain; coma; confusion; coughing up blood; dark urine; diarrhea; difficult or painful urination; dry cough; fever, chills, or sore throat; menstrual changes; mental or mood changes; mouth sores; one-sided weakness; red, swollen, peeling, or blistered skin; seizures; severe or persistent nausea or vomiting; shortness of breath; speech changes; unusual bleeding or bruising; unusual pain and discoloration of the skin; unusual tiredness or weakness; vision changes or vision loss; yellowing of skin or eyes.

Please seek medical attention immediately if you experience any of these severe side effects.
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